CPLX3 Antibody, FITC conjugated

Code CSB-PA851972LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CPLX3 Polyclonal antibody
Uniprot No.
Target Names
CPLX3
Alternative Names
CPLX3 antibody; Nbla11589Complexin-3 antibody; Complexin III antibody; CPX III antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Complexin-3 protein (1-155AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion. Required for the maintenance of synaptic ultrastructure in the adult retina. Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina. Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release.
Gene References into Functions
  1. CPX acts sequentially on assembling SNAREpins, first facilitating zippering by nearly doubling the distance at which v- and t-SNAREs can engage and then clamping them into a half-zippered fusion-incompetent state. PMID: 21785413
Subcellular Location
Cell junction, synapse. Cell membrane; Lipid-anchor.
Protein Families
Complexin/synaphin family
Database Links

HGNC: 27652

OMIM: 609585

KEGG: hsa:594855

STRING: 9606.ENSP00000378464

UniGene: Hs.187694

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